I-Polyethylene Glycol 800: Kusetshenziswa kuphi futhi kusetshenziswa kuphi?

I-Polyethylene Glycol 800, noma i-PEG800 imfishane, iyingxenye ye-polymer eyakhiwe yi-polymerization ye-ethylene oxide namanzi. I-PEG800 incibilikisa kakhulu ku-solvents yePolar enjengamanzi, i-ethanol ne-acetone, futhi ingancibilika ngokushesha kulezi zinhlaka zokwenza uhlelo olufanayo. Lesi sici senza kube yi-solvent enhle noma i-solvent emasimini amaningi.

Ekushiseni okujwayelekile, izakhiwo zamakhemikhali ze-PEG800 zizinzile futhi azithambekele ekuphendukeni kwe-hydrolysis. Lokhu kusho ukuthi ngesikhathi sokugcina, kungagcina ukwakheka kwayo kwamakhemikhali nokusebenza kwayo kungashintshiwe isikhathi eside, kunciphisa ubungozi bokuwohloka komkhiqizo okubangelwa ushintsho lwamakhemikhali.

I-PEG800 inokucasulwa okuphansi kakhulu esikhunjeni somuntu kanye nolwelwesi lwama-mucous. Kuphephile kakhulu lapho kuthathwe ngomlomo noma kusetshenziswe ngokwezifiso futhi kuhlangana namazinga okudla aqinile kanye namazinga ebanga lemithi. Uma kuqhathaniswa nesikhonkwane esiphansi-isisindo se-molecular (njenge-PEG200 no-300), i-PEG800 inokuvuleka okuphezulu nemiphumela yokuqina kanye nokuqina, futhi isetshenziswa kabanzi kwimikhiqizo yokunakekelwa kwesikhumba.

Ngesikhathi sokucutshungulwa kwenjoloba, ukungezwa kwe-PEG800 kunganciphisa kakhulu ukungqubuzana kwangaphakathi phakathi kwama-molecule enjoloba. Ngesikhathi sesigaba sokuxuba kwerabha, kusiza ama-ejenti ahlukahlukene ahlanganisiwe (afana nama-ejenti ahlukahlukene, ama-accelerator, ama-filler, njll.) Ukuze ahlakazeke ngokulinganayo ku-matrix yerabha, ethuthukisa ukusebenza kahle nekhwalithi. I-PEG800 nayo ivame ukusetshenziselwa ukugcoba izindwangu.

I-Dotachem inenzuzo enkulu ekuhlinzekweni kwe-PEG800. Sinohlelo oluqinile lokulawula ikhwalithi, eliqinisekisa ikhwalithi ezinzile yemikhiqizo ye-PEG800 ekhiqizwa yiDotachem. Zonke izinkomba zihlangana noma zize zidlule ezindinganisweni zezimboni, kuqinisekisa ukuthi wonke amaqembu we-PEG800 atholwe amakhasimende anekhwalithi ethembekile. Uyemukelwa ukuvakashelaIkhasi lomkhiqizo we-PEG800yenkampani ye-Dotachem ukuze ufunde imininingwane eminingi yomkhiqizo nemininingwane ye-oda.