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I-I-Polyethylene glycol (PEG)iyi-polymer ephezulu yamangqamuzana encibilika emanzini eyakhiwe yi-polymerization ye-ethylene oxide. Ngenxa ye-hydrophilicity yayo enhle kakhulu, i-biocompatibility kanye nokuzinza kwamakhemikhali, isetshenziswa kakhulu ezimbonini eziyinhloko ezifana nemithi, amakhemikhali ansuku zonke, ezolimo, irabha kanye nezindwangu.
Njengomphakeli ochwepheshe ozinikele emkhakheni wamakhemikhali amahle, i-Dotachem inikeza uhla oluphelele lwemikhiqizo ye-PEG enesisindo samangqamuzana asuka ku-200 kuya ku-8000+.
Izici ezibonakalayo ze-PEG zincike kakhulu esisindweni sayo samangqamuzana.
I-PEG-200 kuya ku-PEG-600: Isisindo esiphansi samangqamuzana, uketshezi. Zine-viscosity ephansi kanye ne-solubility enhle kakhulu yamanzi, futhi zivame ukusetshenziswa njengezincibilikisi ezinhle kakhulu, ama-plasticizers nama-humectants, asetshenziswa kabanzi ekulungiseleleni uketshezi lwezimonyo kanye nemithi.
I-PEG-1000 kuya ku-PEG-4000: Isisindo samangqamuzana amaphakathi, okuqinile kwe-waxy. Njengoba isisindo samangqamuzana sikhula, kanjalo ne-viscosity nendawo yokuncibilika. Isibonelo, i-PEG-3350 iyisizinda se-suppository kanye ne-ointment esetshenziswa kakhulu kwezemithi, ehlinzeka ngokwakheka okuhle nokusebenza kokukhishwa kwezidakamizwa.
I-PEG-6000 nangaphezulu: Isisindo samangqamuzana aphezulu, okuqinile. Inokuqina okuphezulu nendawo yokuncibilika, futhi ivamise ukusetshenziswa njengosizo lokucubungula insimbi, okokugcoba kwethebhulethi noma i-ejenti yokulinganisa yezindwangu, ehlinzeka ngokugcobisa okuhle kakhulu kanye nemiphumela yokuhlakazeka.
Ukukhetha umphakeli we-PEG othembekile kubaluleke kakhulu. Ukukhetha kahle ukucaciswa kwesisindo se-molecular nokuqinisekisa ukuhlanzeka okuphezulu nokuzinza kwenqwaba yomkhiqizo kuyadingeka ukuze kusetshenziswe ngokugcwele ukusebenza kwe-PEG enqubweni yokukhiqiza.
I-Dotachem inganikeza uhla oluphelele lwemikhiqizo evelaI-PEG-200 kuya ku-PEG-20000, ukuhlangabezana nezidingo zakho ezihlukahlukene kusukela kwezimonyo, ezemithi kuya kwezinhlelo zokusebenza zezimboni. Siyaqinisekisa ukuthi yonke iqoqo lemikhiqizo inokusebenza kwekhwalithi ephezulu. Sicela uzizwe ukhululekile ukuxhumana nathi nganoma yisiphi isikhathi ukuze uthole ikhathalogi yomkhiqizo enemininingwane kanye nokubonisana nobuchwepheshe.
